| General Information of Drug Metabolite (DM) (ID: DM002406) |
| DM Name |
Cytochrome P-450-troleandomycin
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Demethylation |
Troleandomycin
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Troleandomycin |
DR1652
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Approved |
Acute upper respiratory infection |
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| References |
| 1 |
Inactivation of cytochrome P-450 by a troleandomycin metabolite. Protective role of glutathione J Pharmacol Exp Ther. 1983 Mar;224(3):685-91.
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