| General Information of Drug Metabolite (DM) (ID: DM002464) |
| DM Name |
AZD-2171 metabolite M2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 (CYP)
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DMEN060
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| Unclear - Unclear |
AZD-2171
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| AZD-2171 |
DR1886
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Phase 3 |
Lung cancer |
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| References |
| 1 |
In vitro hepatic metabolism of cediranib, a potent vascular endothelial growth factor tyrosine kinase inhibitor: interspecies comparison and human enzymology. Drug Metab Dispos. 2010 Oct;38(10):1688-97.
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