General Information of Drug Metabolite (DM) (ID: DM002506)
DM Name
BPI-2009 metabolite M11
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2D6 (CYP2D6) DME0009 Oxidation - Hydroxylation BPI-2009 [1]
Full List of Drug(s) That Produce This DM By Metabolism
BPI-2009 DR0851 Phase 3 Lung cancer
References
1 Metabolic pathway of icotinib in vitro: the differential roles of CYP3A4, CYP3A5, and CYP1A2 on potential pharmacokinetic drug-drug interaction. J Pharm Sci. 2018 Apr;107(4):979-983.

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