| General Information of Drug Metabolite (DM) (ID: DM002573) |
| DM Name |
Isoflavone glucuronide metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronyltransferase (UGT)
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DMEN064
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| Conjugation - Glucuronidation |
Isoflavone
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[1] , [2] , [3] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Isoflavone |
DR2435
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Phase 4 |
Asthma |
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| References |
| 1 |
Bioavailability of isoflavones J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Sep 25;777(1-2):203-10. doi: 10.1016/s1570-0232(02)00347-1.
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| 2 |
Glucuronides are the main isoflavone metabolites in women J Nutr. 2003 Feb;133(2):399-404. doi: 10.1093/jn/133.2.399.
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| 3 |
Comprehensive Evaluation of Metabolism and the Contribution of the Hepatic First-Pass Effect in the Bioavailability of Glabridin in Rats. J Agric Food Chem. 2023 Feb 1;71(4):1944-1956. doi: 10.1021/acs.jafc.2c06460.
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