| General Information of Drug Metabolite (DM) (ID: DM002628) |
| DM Name |
Lynestrenol metabolite M1/Lynestrenol metaboliteM2
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - Hydroxylation |
Lynestrenol
|
[1] |
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME0021
|
| Oxidation - Hydroxylation |
Lynestrenol
|
[1] |
|
|
|
|
|
|
|
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - Dihydroxylation |
Lynestrenol
|
[1] |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Unclear - Unclear |
Lynestrenol
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Lynestrenol |
DR0997
|
Phase 4 |
Transsexualism |
|
|
| References |
| 1 |
Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone. J Steroid Biochem Mol Biol. 2008 May;110(1-2):56-66.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
