| General Information of Drug Metabolite (DM) (ID: DM002740) |
| DM Name |
Peficitinib metabolite MH1
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Nicotinamide N-methyltransferase (NNMT)
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DME0445
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| Unclear - Unclear |
Peficitinib
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[1] |
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Sulfotransferase 2A1 (SULT2A1)
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DME0074
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| Unclear - Unclear |
Peficitinib
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Peficitinib |
DR1774
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Phase 4 |
Rheumatoid arthritis |
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| References |
| 1 |
Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects With Normal and Impaired Hepatic Function Clin Pharmacol Drug Dev. 2020 Aug;9(6):699-708. doi: 10.1002/cpdd.751.
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