General Information of Drug Metabolite (DM) (ID: DM002768) |
DM Name |
9-Aminocamptothecin metabolite M2
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Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
DME(s) Producing This DM through Metabolism |
DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
Cytochrome P450 1A1 (CYP1A1)
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DME0006
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| Unclear - Unclear |
NSC-603071
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[1] |
Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
NSC-603071
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[1] |
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DME(s) Metabolizing This DM |
DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
Cytochrome P450 1A1 (CYP1A1)
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DME0006
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| Unclear - Unclear |
NSC-603071
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[1] |
Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
NSC-603071
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[1] |
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Full List of Drug(s) That Produce This DM By Metabolism |
NSC-603071 |
DR1862
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Phase 2 |
Ovarian cancer |
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References |
1 |
Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor 9-aminocamptothecin: impact on cancer therapy. Int J Oncol. 2014 Aug;45(2):877-86.
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