| General Information of Drug Metabolite (DM) (ID: DM002809) |
| DM Name |
Ketoconazole ketone hydroxyl intermediate
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - N-Dealkylation |
Ketoconazole
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - N-Dealkylation |
Ketoconazole
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Ketoconazole |
DR0906
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Approved |
Dermatophytosis |
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| References |
| 1 |
Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.
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