| General Information of Drug Metabolite (DM) (ID: DM003164) |
| DM Name |
Cinnarizine metabolite M2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Hydrolyzationn |
Cinnarizine
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Cinnarizine |
DR0329
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Phase 4 |
Haemorrhagic stroke |
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| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
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