| General Information of Drug Metabolite (DM) (ID: DM003348) |
| DM Name |
NE-10064 Metabolite M4
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - N-oxidation |
NE-10064
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Oxidation - N-oxidation |
NE-10064
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[1] |
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Flavin-containing monooxygenase (FMO)
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DMEN075
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| Oxidation - N-oxidation |
NE-10064
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| NE-10064 |
DR0167
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Phase 3 |
Cardiac arrhythmia |
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| References |
| 1 |
The metabolic profile of azimilide in man: in vivo and in vitro evaluations. J Pharm Sci. 2005 Sep;94(9):2084-95.
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