| General Information of Drug Metabolite (DM) (ID: DM003606) |
| DM Name |
SQ-109 Metabolite M4-2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Multi-steps Reaction - Ring oxidation; Epoxidation; rearrangement |
SQ-109
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Multi-steps Reaction - Ring oxidation; Epoxidation; rearrangement |
SQ-109
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| SQ-109 |
DR1852
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Phase 2 |
Pulmonary tuberculosis |
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| References |
| 1 |
Interspecies pharmacokinetics and in vitro metabolism of SQ109. Br J Pharmacol. 2006 Mar;147(5):476-85.
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