| General Information of Drug Metabolite (DM) (ID: DM003608) |
| DM Name |
Mono-N-demethyl ferroquine
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
SSR-97193
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Unclear - Unclear |
SSR-97193
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| SSR-97193 |
DR1828
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Phase 2 |
Malaria |
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| References |
| 1 |
In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum. Drug Metab Dispos. 2006 Apr;34(4):667-82.
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