General Information of Drug Metabolite (DM) (ID: DM004552)
DM Name
2-{[4-(1-hydroxypropan-2-yl)cyclohexyl]formamido}-3-phenylpropanoic acid
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2C9 (CYP2C9) DME0019 Oxidation - Aliphatic hydroxylation Nateglinide [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Aliphatic hydroxylation Nateglinide [1]
Full List of Drug(s) That Produce This DM By Metabolism
Nateglinide DR1132 Approved Diabetes mellitus
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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