| General Information of Drug Metabolite (DM) (ID: DM004552) |
| DM Name |
2-{[4-(1-hydroxypropan-2-yl)cyclohexyl]formamido}-3-phenylpropanoic acid
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - Aliphatic hydroxylation |
Nateglinide
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Aliphatic hydroxylation |
Nateglinide
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Nateglinide |
DR1132
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Approved |
Diabetes mellitus |
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| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
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