General Information of Drug Metabolite (DM) (ID: DM004584)
DM Name
4-(o-carboxybenzamido)glutaramic acid
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Nonenzymatical (Non-ME) DMEN081 Conjugation - Amide Hydrolyation Thalidomide [1]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Nonenzymatical (Non-ME) DMEN081 Conjugation - Amide Hydrolyation Thalidomide [1]
Nonenzymatical (Non-ME) DMEN081 Conjugation - Amide Hydrolyation Thalidomide [2]
Nonenzymatical (Non-ME) DMEN081 Conjugation - Amide Hydrolyation Thalidomide [2]
Full List of Drug(s) That Produce This DM By Metabolism
Thalidomide DR1572 Approved Breast cancer
References
1 Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites
2 Thalidomide metabolism and hydrolysis: mechanisms and implications

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.