Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM004776)
DM Name	Oxygen
Synonyms	7782-44-7\|O\|Oxygen\|Molecular oxygen\|oxygen molecule\|Dioxygen\|Pure oxygen\|Oxygenium\|Hyperoxia\|Liquid oxygen\|Oxygen-16\|Oxygen, liquified\|oxygene\|Oxygenium medicinale\|Sauerstoff\|Oxygen (liquid)\|oxigeno\|Compressed oxygen\|CCRIS 1228\|Oxygene [French]\|Oxigeno [Spanish]\|HSDB 5054\|dioxygene\|Disauerstoff\|Dioxygenyl ion\|O2\|Oxygen USP\|EINECS 231-956-9\|Oxygen, compressed\|UN1072\|UN1073\|Oxygen [USP]\|RNS60 COMPONENT OXYGEN\|INS NO.948\|RNS-60 COMPONENT OXYGEN\|UNII-S88TT14065\|CHEBI:15379\|INS-948\|E-948\|S88TT14065\|E948\|Peroxide Ion\|LOX\|DTXSID2037681\|E 948\|OXYGEN (MART.)\|OXYGEN [MART.]\|Oxygen, compressed [UN1072] [Nonflammable gas]\|OXY\|OXYGEN (EP MONOGRAPH)\|OXYGEN [EP MONOGRAPH]\|OXYGEN (USP MONOGRAPH)\|OXYGEN [USP MONOGRAPH]\|(OO)\|[OO]\|Oxygen, refrigerated liquid (cryogenic liquid) [UN1073] [Nonflammable gas]\|Oxygen 16\|dioxidanediyl\|oxygen monoxide\|Oxigeno gaseoso\|Peroxy radical\|singlet dioxygen\|triplet dioxygen\|Oxygen (DOT\|Oxygen, USP\|Oxygen 93 percent\|singlet molecular oxygen\|triplet molecular oxygen\|OXY (CHRIS Code)\|Oxygen (8CI,9CI)\|OXYGEN [VANDF]\|OXYGEN [HSDB]\|OXYGEN [INCI]\|OXYGEN [JAN]\|Oxygen (JP17/USP)\|OXYGEN [WHO-DD]\|OXYGEN [WHO-IP]\|OXYGEN [MI]\|dioxygen(2.) (triplet)\|Oxygen, >=99.6%\|OXYGEN [GREEN BOOK]\|OXYGEN, (COMPRESSED)\|Oxygen, >=99.998%\|CHEMBL1234886\|DTXCID0017681\|CHEBI:26689\|CHEBI:27140\|OXYGENIUM [WHO-IP LATIN]\|NA1072\|NA1073\|DB09140\|UN 1072\|UN 1073\|Oxygen, Messer(R) CANGas, 99.999%\|LS-101123\|(1)O2\|C00007\|D00003\|O2(2.)\|Oxygen, refrigerated liquid (cryogenic liquid)\|Oxygen, compressed [UN1072] [Nonflammable gas]\|(O2)(..)\|(O2)(2.)\|Q5203615\|AQUANAL(TM)-plus oxygen (O2) 1-12 mg/L, refill pack for 37428\|AQUANAL(TM)-plus oxygen (O2) 1-12 mg/L, test set with color comparator\|Oxygen, refrigerated liquid (cryogenic liquid) [UN1073] [Nonflammable gas]
Structure
Structure	3D MOL			2D MOL
Pharmaceutical Properties	Molecular Weight		31.999	Topological Polar Surface Area		34.1
	Heavy Atom Count		2	Rotatable Bond Count		0
	Hydrogen Bond Donor Count		0	Hydrogen Bond Acceptor Count		2
PubChem CID	977
Complexity	0
Formula	O2
Canonical SMILES	O=O
InChI	InChI=1S/O2/c1-2
InChIKey	MYMOFIZGZYHOMD-UHFFFAOYSA-N
IUPAC name	molecular oxygen

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Catalase (CAT)	DME0090	Hydrogen peroxide	Reduction - Reduction	Hydrogen peroxide	[1]
Cellular glutathione peroxidase (GPX1)	DME0147	Hydrogen peroxide	Reduction - Reduction	Hydrogen peroxide	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Hydrogen peroxide		DR0832	Approved		Emphysema

Nitrite		DR2117	Investigative		Discovery agent

References
1	Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes. Blood. 1989 Jan;73(1):334-9.

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