General Information of Drug Metabolite (DM) (ID: DM005009)
DM Name
ETC-1002-CoA
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Very long-chain acyl-CoA synthetase (SLC27A2) DMEN256 Unclear - Unclear Bempedoic acid [1] , [2]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Unclear - Unclear Bempedoic acid [3]
Full List of Drug(s) That Produce This DM By Metabolism
Bempedoic acid DR5353 Approved Hypertriglyceridaemia
References
1 Bempedoic Acid (ETC-1002): A Current Review
2 The Disposition and Metabolism of Bempedoic Acid, a Potent Inhibitor of ATP Citrate Lyase, in Healthy Human Subjects
3 DrugBank(Pharmacology-Metabolism):Bempedoic acid

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