General Information of Drug Metabolite (DM) (ID: DM005800)
DM Name
Tranilast glucuronide
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004 Conjugation - Glucuronidation Tranilast [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Tranilast DR1628 Phase 4 Conjunctivitis
References
1 Glucuronidation of antiallergic drug, Tranilast: identification of human UDP-glucuronosyltransferase isoforms and effect of its phase I metabolite. Drug Metab Dispos. 2007 Apr;35(4):583-9.
2 Simultaneous determination of tranilast and metabolites in plasma and urine using high-performance liquid chromatography

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