| General Information of Drug Metabolite (DM) (ID: DM006480) |
| DM Name |
EPX-100 M1
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Oxidationn |
EPX-100
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidationn |
EPX-100
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Oxidation - Oxidationn |
EPX-100
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| EPX-100 |
DR2274
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Preclinical |
Dravet syndrome |
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| References |
| 1 |
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction. J Pharmacol Exp Ther. 2013 Feb;344(2):388-96.
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