| General Information of Drug Metabolite (DM) (ID: DM006858) |
| DM Name |
EBP-994 M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
EBP-994
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Unclear - Unclear |
EBP-994
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| EBP-994 |
DR1861
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Phase 2 |
Progeria |
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| References |
| 1 |
Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar). Drug Metab Dispos. 2006 Apr;34(4):628-35.
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