| General Information of Drug Metabolite (DM) (ID: DM007053) |
| DM Name |
Pirprofen glucuronide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Conjugation - Glucuronidation |
Pirprofen
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Pirprofen |
DR1304
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Phase 4 |
Rheumatoid arthritis |
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| References |
| 1 |
High-performance liquid chromatographic determination of pirprofen and five of its metabolites in human plasma without hydrolysis and in human urine before and after chemical hydrolysis
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| 2 |
Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes. Drug Metab Dispos. 1990 Sep-Oct;18(5):692-7.
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