General Information of Drug Metabolite (DM) (ID: DM017026)
DM Name
Loxoprofen gel metabolite M16
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Unclear - Unclear Loxoprofen gel [1] , [2]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Unclear - Unclear Loxoprofen gel [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Loxoprofen gel DR5328 Approved Inflammation
References
1 Identification of sulfonyl-loxoprofen as novel phase 2 conjugate in rat
2 Exploring the metabolism of loxoprofen in liver microsomes: the role of cytochrome P450 and UDP-glucuronosyltransferase in its biotransformation. Pharmaceutics. 2018 Aug 2;10(3). pii: E112.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.