| General Information of Drug Metabolite (DM) (ID: DM017608) |
| DM Name |
Sotorasib Metabolite M10
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Bleomycin hydrolase (BLMH)
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DME0086
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| Hydrolysis - Hydrolysis |
Sotorasib
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Sotorasib |
DR3515
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Phase 3 |
Lung cancer |
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| References |
| 1 |
Absorption, Distribution, Metabolism, and Excretion of [(14)C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
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