General Information of Drug Metabolite (DM) (ID: DM017911)
DM Name
Rilpivirine M3
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Hydroxylation Rilpivirine hydrochloride [1]
Cytochrome P450 3A5 (CYP3A5) DME0012 Oxidation - Hydroxylation Rilpivirine hydrochloride [1]
Full List of Drug(s) That Produce This DM By Metabolism
Rilpivirine hydrochloride DR1424 Approved Human immunodeficiency virus infection
References
1 Human biotransformation of the nonnucleoside reverse transcriptase inhibitor rilpivirine and a cross-species metabolism comparison. Antimicrob Agents Chemother. 2013 Oct;57(10):5067-79.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.