Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM017950)
DM Name
Mono-BVMG ()
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME0041
MPC-4326
Conjugation - Glucuronidation MPC-4326 [1]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME0041
MPC-4326
Conjugation - Glucuronidation MPC-4326 [2]
UDP-glucuronosyltransferase 1A4 (UGT1A4) DME0048
MPC-4326
Conjugation - Glucuronidation MPC-4326 [1]
UDP-glucuronosyltransferase 1A4 (UGT1A4) DME0048
MPC-4326
Conjugation - Glucuronidation MPC-4326 [2]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040
MPC-4326
Conjugation - Glucuronidation MPC-4326 [1]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040
MPC-4326
Conjugation - Glucuronidation MPC-4326 [2]
Full List of Drug(s) That Produce This DM By Metabolism
MPC-4326 DR1856 Phase 2 Human immunodeficiency virus infection
References
1 Glucuronidation of anti-HIV drug candidate bevirimat: identification of human UDP-glucuronosyltransferases and species differences
2 Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection. Antivir Chem Chemother. 2008;19(3):107-13.

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