| General Information of Drug Metabolite (DM) (ID: DM017951) |
| DM Name |
Mono-BVMG ()
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Conjugation - Glucuronidation |
MPC-4326
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[1] |
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UDP-glucuronosyltransferase 1A4 (UGT1A4)
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DME0048
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| Conjugation - Glucuronidation |
MPC-4326
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[1] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
MPC-4326
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[1] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
MPC-4326
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[2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| MPC-4326 |
DR1856
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Phase 2 |
Human immunodeficiency virus infection |
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| References |
| 1 |
Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection. Antivir Chem Chemother. 2008;19(3):107-13.
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| 2 |
Glucuronidation of anti-HIV drug candidate bevirimat: identification of human UDP-glucuronosyltransferases and species differences
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