General Information of Drug Metabolite (DM) (ID: DM018043)
DM Name
(E)-10-hydroxyamitriptyline
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2D6 (CYP2D6) DME0009 Unclear - Unclear Amitriptyline hydrochloride [1] , [2]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Cytochrome P450 2D6 (CYP2D6) DME0009 Unclear - Unclear Amitriptyline hydrochloride [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Amitriptyline hydrochloride DR0095 Approved Depression
References
1 CYP2D6 and CYP2C19 genotypes and amitriptyline metabolite ratios in a series of medicolegal autopsies
2 Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype

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