Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM018113)
DM Name	Quinine sulfate Metabolite M1
Structure
Structure	3D MOL is unavailable	2D MOL is unavailable

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 3A4 (CYP3A4)	DME0001	Quinine sulfate	Oxidation - Hydroxylation	Quinine sulfate	[1]
Mephenytoin 4-hydroxylase (CYP2C19)	DME0021	Quinine sulfate	Oxidation - Hydroxylation	Quinine sulfate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Quinine sulfate		DR1385	Approved		Malaria

References
1	CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever

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