General Information of Drug Metabolite (DM) (ID: DM018119)
DM Name
RaltegravirCglucuronide
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004 Unclear - Unclear Raltegravir potassium [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Raltegravir potassium DR1390 Approved Human immunodeficiency virus infection
References
1 Quantification of the HIV-integrase inhibitor raltegravir and detection of its main metabolite in human plasma, dried blood spots and peripheral blood mononuclear cell lysate by means of high-performance liquid chromatography tandem mass spectrometry
2 Impact of UGT1A1 polymorphisms on Raltegravir and its glucuronide plasma concentrations in a cohort of HIV-1 infected patients

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