| General Information of Drug Metabolite (DM) (ID: DM018307) |
| DM Name |
Inotersen Metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Endonuclease (ENDO)
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DMEN805
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| Unclear - Unclear |
Inotersen
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Exonuclease 1 (EXO1)
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DMEN806
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| Unclear - Unclear |
Inotersen
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Inotersen |
DR5033
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Approved |
Amyloidosis |
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| References |
| 1 |
Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration-Approved Antisense Oligonucleotide Drugs
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