| General Information of Drug Metabolite (DM) (ID: DM018498) |
| DM Name |
Pexacerfont Metabolite M8
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
Pexacerfont
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Unclear - Unclear |
Pexacerfont
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Pexacerfont |
DR3374
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Phase 2/3 |
Anxiety disorder |
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| References |
| 1 |
In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist
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