| General Information of Drug Metabolite (DM) (ID: DM018967) |
| DM Name |
LNP023 Metabolite M3
|
| Structure |
|
|
3D MOL is unavailable
|
2D MOL is unavailable
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2C8 (CYP2C8)
|
DME0018
|
| Oxidation - Oxidation |
LNP023
|
[1] , [2] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| LNP023 |
DR3488
|
Phase 3 |
IgA nephropathy |
|
|
| References |
| 1 |
Pharmacokinetics and metabolism of LNP023 in rats by liquid chromatography combined with electrospray ionization-tandem mass spectrometry
|
| 2 |
Absorption, Distribution, Metabolism, and Excretion of [(14)C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
