| General Information of Drug Metabolite (DM) (ID: DM018968) |
| DM Name |
LNP023 Metabolite M2
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Conjugation - Glucuronidation |
LNP023
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| LNP023 |
DR3488
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Phase 3 |
IgA nephropathy |
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| References |
| 1 |
Pharmacokinetics and metabolism of LNP023 in rats by liquid chromatography combined with electrospray ionization-tandem mass spectrometry
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| 2 |
Absorption, Distribution, Metabolism, and Excretion of [(14)C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies
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