General Information of Drug Metabolite (DM) (ID: DM019086)
DM Name
TAK-272 Metabolite M1
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear TAK-272 [1]
Cytochrome P450 3A5 (CYP3A5) DME0012 Unclear - Unclear TAK-272 [1]
Full List of Drug(s) That Produce This DM By Metabolism
TAK-272 DR3278 Phase 2 Type-2 diabetes
References
1 Pharmacokinetics and Safety After a Single Dose of Imarikiren in Subjects with Renal or Hepatic Impairment

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