General Information of Drug Metabolite (DM) (ID: DM019140)
DM Name
Tivantinib Metabolite M9
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Oxidation Tivantinib [1]
Cytochrome P450 3A5 (CYP3A5) DME0012 Oxidation - Oxidation Tivantinib [1]
Full List of Drug(s) That Produce This DM By Metabolism
Tivantinib DR3448 Phase 3 Solid tumour/cancer
References
1 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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