| General Information of Drug Metabolite (DM) (ID: DM019425) |
| DM Name |
N-desmethyl masitinib(M485)
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C8 (CYP2C8)
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DME0018
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| Unclear - Unclear |
Masitinib
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
Masitinib
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Masitinib |
DR3536
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Phase 3 |
Amyotrophic lateral sclerosis |
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| References |
| 1 |
Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib
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