| General Information of Drug Metabolite (DM) (ID: DM020013) |
| DM Name |
Zafirlukast metabolite M6
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Unclear - Unclear |
Zafirlukast
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[1] , [2] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
Zafirlukast
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Zafirlukast |
DR1723
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Approved |
Asthma |
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| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
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| 2 |
Metabolism and excretion of zafirlukast in dogs, rats, and mice
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