Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM000183)
DM Name	Fingolimod carboxylic acid metabolite

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 4F2 (CYP4F2)	DME0025	Fingolimod	Oxidation - Hydroxylation	Fingolimod	[1]
Cytochrome P450 4F2 (CYP4F2)	DME0025	Fingolimod hydrochloride	Oxidation - Hydroxylation	Fingolimod hydrochloride	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Fingolimod	DR0696	Approved	Multiple sclerosis

Fingolimod hydrochloride	DR0697	Approved	Multiple sclerosis

References
1	Clinical pharmacokinetics of fingolimod Clin Pharmacokinet. 2012 Jan 1;51(1):15-28. doi: 10.2165/11596550-000000000-00000.

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