| General Information of Drug Metabolite (DM) (ID: DM001299) |
| DM Name |
Hydroxylated and dealkylated products
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C8 (CYP2C8)
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DME0018
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| Oxidation - Oxidation |
Selexipag
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidation |
Selexipag
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Selexipag |
DR1471
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Approved |
Pulmonary hypertension |
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| References |
| 1 |
FDA LABEL:elexipag
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