Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM002266)
DM Name	Norethindrone acetate metabolite M3

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 3A4 (CYP3A4)	DME0001	Norethindrone acetate metabolite M1,M2	Oxidation - Dihydroxylation	Norethindrone acetate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Norethindrone acetate		DR1750	Approved		Menorrhagia

References
1	Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone. J Steroid Biochem Mol Biol. 2008 May;110(1-2):56-66.

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