| General Information of Drug Metabolite (DM) (ID: DM003041) |
| DM Name |
Hydroxyvemurafenib
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - Hydroxylation |
Vemurafenib
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Vemurafenib |
DR1677
|
Approved |
Melanoma |
|
|
| References |
| 1 |
Novel rapid liquid chromatography tandem masspectrometry method for vemurafenib and metabolites in human plasma, including metabolite concentrations at steady state Biomed Chromatogr. 2016 Aug;30(8):1234-9. doi: 10.1002/bmc.3672.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
