General Information of Drug Metabolite (DM) (ID: DM003052)
DM Name
NH3
Synonyms
ammonia|7664-41-7|azane|Ammonia gas|Nitro-sil|Ammoniakgas|Ammonia anhydrous|Anhydrous ammonia|Ammonia, anhydrous|Ammoniak|Liquid Ammonia|AM-Fol|Ammoniak Kconzentrierter|ammoniac|Aqueous ammonia|Caswell No. 041|Amoniak [Polish]|Ammoniac [French]|Ammoniak [German]|Refrigerent R717|amoniaco|Ammoniaca [Italian]|Ammoniaca|Amoniak|CCRIS 2278|HSDB 162|Ammonia (conc 20% or greater)|NH3|R 717 (ammonia)|EPA Pesticide Chemical Code 005302|R 717|EINECS 231-635-3|UN1005|Ammonia (anhydrous)|UNII-5138Q19F1X|CHEBI:16134|Ammonia, 7M in methanol|5138Q19F1X|Ammonia anhydrous, 99.98%|DTXSID0023872|EC 231-635-3|MFCD00011418|AMMONIA (II)|AMMONIA [II]|R-717|(NH3)|[NH3]|H3-N|Ammonia; Ammonia solution concentrated|8007-57-6|Ammonia Standard: NH3 @ 10 microg/mL in H2O|Ammonia Standard: NH3 @ 100 microg/mL in H2O|Ammonia Standard: NH3 @ 1000 microg/mL in H2O|Ammonia Standard: NH3 @ 10000 microg/mL in H2O|Ammoniakk|Ammoniale|tertiaeres Amin|Aminyl radical|ammonia ca|primaeres Amin|Ammonia inhalant|Ammonia,aromatic|Ammoniacum gummi|Amoniaco anhidro|sekundaeres Amin|Ammonia (total)|anyhydrous ammonia|ammoniac, anhydre|Ammonia (ACN|Ammonia (aqueous)|NH4|UNX|Ammonia (as N)|Ammonia - anhydrous|CONTEST Group D|10 - Nutrients|37 - Ammonia|Refrigerant gas 717|AMA (CHRIS Code)|AMMONIA [VANDF]|S18 - MCerts|60 - MCerts|AMMONIA [INCI]|Ammonia (8CI,9CI)|Ammonia water (JP15)|Aromatic ammonia vaporole|CONTEST Group B Full|AMMONIA [MI]|InChI=1/H3N/h1H|Ammonia, 2M in methanol|Dowex(R) 66 free base|AMMONIA [WHO-DD]|CONTEST Group B Reduced|Ammonia, 0.5M in THF|Aromatic Ammonia, Vaporole|D0FT7Y|AMMONIA, (ANHYDROUS)|82168-61-4|DTXCID803872|N H3|CHEMBL1160819|DTXSID80420101|IYQDUNKKQCFKJG-UHFFFAOYSA-N|UCPKOFQHNMRORR-UHFFFAOYSA-N|UFNYKIJQJNNVKS-UHFFFAOYSA-N|XBPJHBIOSSFGCU-UHFFFAOYSA-N|ZBEYHISPVKPLHP-UHFFFAOYSA-N|Ammonia (conc. 20% or greater)|DTXSID801029786|NH(3)|2-Methylamino-5-nitro-benzonitrile|Ammonia, anhydrous, >=99.98%|ANHYDROUS AMMONIA, LIQUEFIED|AMMONIA, ANHYDROUS, LIQUEFIED|NA1005|NA2073|AKOS015916403|Ammonia anhydrous 170g Lecture bottle|Ammonia solution 1.0 M in isopropanol|NH3 as N: 1000microg/mL in H20|17D - Ammonia, Phosphate and Nitrogen|AMMONIA (ANHYDROUS) (LIQUEFIED)|USEPA/OPP Pesticide Code: 005302|Ammonia, puriss., anhydrous, >=99.9%|LS-16633|02H - Nutrients and Others - Hard Water|02S - Nutrients and Others - Soft Water|Ammonia, puriss., anhydrous, >=99.95%|Q4087|C00014|D02916|Dowex(R) Marathon(TM) WBA free base, free base|Q4832241|Q6004010|Q27110025|2HP - Nutrients and Others in hard, potable (treated) water|2SP - Nutrients and Others in soft, potable (treated) water|StratoSpheres(TM) PL-AMS resin, 100-200 mesh, extent of labeling: ~1.0 mmol/g loading, 1 % cross-linked with divinylbenzene|StratoSpheres(TM) PL-AMS resin, 100-200 mesh, extent of labeling: 2.0 mmol/g loading, 1 % cross-linked|StratoSpheres(TM) PL-AMS resin, 30-40 mesh, extent of labeling: 1.0 mmol/g loading, 1 % cross-linked|StratoSpheres(TM) PL-AMS resin, 30-40 mesh, extent of labeling: 2.0 mmol/g loading, 1 % cross-linked|StratoSpheres(TM) PL-AMS resin, 50-100 mesh, extent of labeling: 2.0 mmol/g loading, 1 % cross-linked
Structure
3D MOL 2D MOL
Pharmaceutical Properties Molecular Weight 17.031 Topological Polar Surface Area 1
Heavy Atom Count 1 Rotatable Bond Count 0
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1
PubChem CID
222
Complexity
0
Formula
H3N
Canonical SMILES
N
InChI
InChI=1S/H3N/h1H3
InChIKey
QGZKDVFQNNGYKY-UHFFFAOYSA-N
IUPAC name
azane
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Selenocysteine lyase (SCLY) DME0211 Oxidation - Degradation Selenium [1]
Semicarbazide-sensitive amine oxidase (AOC2) DME0477 Oxidation - Deamination Methylamine [2]
Full List of Drug(s) That Produce This DM By Metabolism
Selenium DR1469 Approved Seborrhoeic dermatitis
Xanthine DR1719 Phase 1 Obstructive sleep apnea
Methylamine DR2042 Investigative Discovery agent
References
1 Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis. 1999 Sep;20(9):1657-66.
2 Deamination of methylamine and angiopathy; toxicity of formaldehyde, oxidative stress and relevance to protein glycoxidation in diabetes

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