| General Information of Drug Metabolite (DM) (ID: DM003429) |
| DM Name |
Quinone methide
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Unclear - Unclear |
CBT-1
|
[1] |
|
Cytochrome P450 3A5 (CYP3A5)
|
DME0012
|
| Unclear - Unclear |
CBT-1
|
[1] |
|
|
|
|
|
|
|
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A5 (CYP3A5)
|
DME0012
|
| Unclear - Unclear |
CBT-1
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| CBT-1 |
DR1570
|
Phase 1 |
Histiocytic sarcoma |
|
|
| Eugenol |
DR1942
|
Investigative |
Discovery agent |
|
|
| References |
| 1 |
CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine. Arch Toxicol. 2016 Jul;90(7):1737-48.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
