Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM004129)
DM Name	WIN 55212-2 Metabolite M1a

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Metabolizing This DM

DME Name	DME ID	Product	Reaction	Related Drug	REF
Epoxide hydrolase 1 (EPHX1)	DME0623	WIN 55212-2 Metabolite M8a	Oxidation - Hydrolyzationn	WIN 55212-2	[1] , [2]

Full List of Drug(s) That Produce This DM By Metabolism
WIN 55212-2		DR1718	Investigative		Anaesthesia

References
1	In vitro metabolism of R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a cannabinoid receptor agonist
2	Toxicokinetics of new psychoactive substances: plasma protein binding, metabolic stability, and human phase I metabolism of the synthetic cannabinoid WIN 55,212-2 studied using in vitro tools and LC-HR-MS/MS

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