General Information of Drug Metabolite (DM) (ID: DM017222)
DM Name
LJN452 metabolite M24
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2C9 (CYP2C9) DME0019 Unclear - Unclear LJN452 [1]
Full List of Drug(s) That Produce This DM By Metabolism
LJN452 DR3268 Phase 2 Primary biliary cholangitis
References
1 Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism

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