General Information of Drug Metabolite (DM) (ID: DM019568)
DM Name
PD-153035 M3
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2D (CYP2D) DMEN826 Oxidation - O-demethylation PD-153035 [1]
Cytochrome P450 3A (CYP3A) DMEN065 Oxidation - O-demethylation PD-153035 [1]
Full List of Drug(s) That Produce This DM By Metabolism
PD-153035 DR2901 Discontinued in Phase 1 Psoriasis vulgaris
References
1 Metabolism of epidermal growth factor receptor targeting probe [11C]PD153035: impact on biodistribution and tumor uptake in rats

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