| General Information of Drug (ID:
DR2858) |
| Drug Name |
Sudan I
|
| Synonyms |
Sudan I; 842-07-9; Solvent Yellow 14; 1-Phenylazo-2-naphthol; C.I. Solvent Yellow 14; 1-(Phenylazo)-2-naphthalenol; Grasal Orange; Spirit Orange; Fast Orange; Oil Orange; Fast Oil Orange; Soudan I; Dunkelgelb; Pyronalorange; Carminaph; Fettorange lg; Cerotinorange G; Organol Orange; Stearix Orange; Fettorange R; Motiorange R; Scharlach B; Calcogas M; Orange Pel; Fettorange 4a; SUDAN 1; Grasan Orange R; Petrol Orange Y; Sansel Orange G; Spirit Yellow I
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| Indication |
Discovery agent
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Investigative
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[1]
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| Structure |
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3D MOL
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2D MOL
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| Cross-matching ID |
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| The Metabolic Roadmap of This Drug |
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| The Full List of Drug Metabolites (DM) of This Drug |
| DM Name |
DM ID |
PubChem ID |
Reaction |
DM Level |
REF |
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1-Amino-2-naphthol
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DM005529
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|
Unclear |
1 |
[4]
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Aniline
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DM004785
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Unclear |
1 |
[4]
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Unclear
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DM009999
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N. A. |
Unclear |
1 |
[2]
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| The Full List of Metabolic Reaction (MR) of This Drug |
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| Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug |
| DME Name |
DME Info |
Species |
Uniprot ID |
EC Number |
REF |
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Cytochrome P450 1A1 (CYP1A1)
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DME0006
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Homo sapiens
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[2]
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Unclear metabolic mechanism (DME-unclear)
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DME1657
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Blautia obeum
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Not Available |
Not Available |
[3]
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| References |
| 1 |
Sudan dyes: are they dangerous for human health? Drug Chem Toxicol. 2013 Jul;36(3):343-52.
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| 2 |
Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes
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| 3 |
Sudan azo dyes and Para Red degradation by prevalent bacteria of the human gastrointestinal tract. Anaerobe. 2010 Apr;16(2):114-9.
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| 4 |
PubChem:Sudan I
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