Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR3465)
Drug Name
Benserazide
Synonyms
benserazide; Serazide; 322-35-0; Benseraszide; Benserazida; Benserazidum; Ro 4-4602; Ro 44602; DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide; Benserazidum [INN-Latin]; Benserazida [INN-Spanish]; Benserazide [USAN:INN:BAN]; DL-Seryltrihydroxybenzylhydrazine; C10H15N3O5; BRN 3984490; DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; CHEBI:64187; DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-; DL-serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
Structure
3D MOL 2D MOL
Pharmaceutical Properties Molecular Weight 257.24 Topological Polar Surface Area 148
Heavy Atom Count 18 Rotatable Bond Count 5
Hydrogen Bond Donor Count 7 Hydrogen Bond Acceptor Count 7
Cross-matching ID
PubChem CID
2327
ChEBI ID
CHEBI:64187
CAS Number
322-35-0
TTD Drug ID
D0X8ED
Formula
C10H15N3O5
Canonical SMILES
C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O
InChI
InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)
InChIKey
BNQDCRGUHNALGH-UHFFFAOYSA-N
The Metabolic Roadmap of This Drug
The Full List of Drug Metabolites (DM) of This Drug
DM Name DM ID PubChem ID Reaction DM Level REF
Trihydroxybenzylhydrazine DM015246
188973
Other reaction - Hydoxylation 1 [1]
The Full List of Metabolic Reaction (MR) of This Drug
MR ID Reactant Product MR Type DME REF
MR009121 Benserazide Trihydroxybenzylhydrazine Other reaction - Hydoxylation COMT [1]
References
1 DrugBank(Pharmacology-Metabolism):Benserazide

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