Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR2486)
Drug Name
Alpha-l-arabinose
Synonyms
Arabinopyranose, alpha-L-; Arabinose l-form; SCHEMBL112371; SRBFZHDQGSBBOR-QMKXCQHVSA-N; UO2PIV2K4C; ZINC1532575; alpha-L-Arabinose; alpha-L-arabinopyranose; 6abp; 7296-55-1; C02604; CHEBI:46987; CHEMBL505348; CTK5D7165; UNII-UO2PIV2K4C
Indication Discovery agent Investigative [1]
Structure
3D MOL 2D MOL
Pharmaceutical Properties Molecular Weight 150.13 Topological Polar Surface Area 90.2
Heavy Atom Count 10 Rotatable Bond Count 0
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 5
Cross-matching ID
PubChem CID
439731
ChEBI ID
CHEBI:46987
CAS Number
7296-55-1
Formula
C5H10O5
Canonical SMILES
C1C(C(C(C(O1)O)O)O)O
InChI
1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3-,4+,5+/m0/s1
InChIKey
SRBFZHDQGSBBOR-QMKXCQHVSA-N
The Metabolic Roadmap of This Drug
The Full List of Drug Metabolites (DM) of This Drug
DM Name DM ID PubChem ID Reaction DM Level REF
GFPS1b DM003787 N. A. Unclear 1 [3]
SGP DM003786 N. A. Unclear 1 [4]
The Full List of Metabolic Reaction (MR) of This Drug
MR ID Reactant Product MR Type DME REF
MR004142 Alpha-l-arabinose SGP Unclear Unclear [4]
MR004143 Alpha-l-arabinose GFPS1b Unclear Unclear [3]
Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug
DME Name DME Info Species Uniprot ID EC Number REF
L-arabinose isomerase (araA) DME1005 Lactobacillus fermentum
D9ILD9_LACFE
5.3.1.4
[2]
References
1 Induction by (alpha)-L-Arabinose and (alpha)-L-Rhamnose of Endopolygalacturonase Gene Expression in Colletotrichum lindemuthianum. Appl Environ Microbiol. 1997 Jun;63(6):2287-92.
2 Protein purification, crystallization and preliminary X-ray diffraction analysis of L-arabinose isomerase from Lactobacillus fermentum CGMCC2921. Acta Crystallogr F Struct Biol Commun. 2015 Jan 1;71(Pt 1):28-33.
3 Structural analysis of anti-tumor heteropolysaccharide GFPS1b from the cultured mycelia of Grifola frondosa GF9801
4 Chemical structure and antioxidant activity of a polysaccharide from Siraitia grosvenorii

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