Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000080)
Formula
XDH
SVG example
Oxidation
Reactant Hypoxanthine Product Xanthine
Reactant Info Product Info
Metabolic Enzyme Xanthine dehydrogenase/oxidase (XDH) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007055 Hypoxanthine Uric acid Conjugation - Glucuronidation Hypoxanthine [1]
MR008772 Hypoxanthine Uric acid Unclear - Unclear Didanosine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008774 Didanosine Xanthine Unclear - Unclear Didanosine [3]
References
1 T3DB:Hypoxanthine
2 Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
3 DrugBank(Pharmacology-Metabolism):Didanosine

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