Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008774)
Formula
SVG example
Unclear
Reactant Didanosine Product Xanthine
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008775 Didanosine 2,3-dideoxyadenosine-5-triphosphate Unclear - Unclear Didanosine [1]
MR008771 Didanosine Hypoxanthine Unclear - Unclear Didanosine [2]
MR008773 Didanosine Uric acid Unclear - Unclear Didanosine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007508 Hypoxanthine Xanthine Unclear Inosine [3]
MR000080 Hypoxanthine Xanthine Oxidation - Oxidation Adenosine [4], [5]
References
1 DrugBank(Pharmacology-Metabolism):Didanosine
2 Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
3 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
4 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
5 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.

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